Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232713 | 0.81 | CA2 (0.31) | GAACA2CA12 | |
| SCHEMBL21241140 | 0.73 | HTT (0.36) | BAZ2BLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28202530 | 0.70 | CA12 (0.35) | GAACA2CA12 | |
| SCHEMBL13574055 | 0.70 | — | — | |
| SCHEMBL24467084 | 0.69 | — | — | |
| SCHEMBL26707512 | 0.68 | BAZ2B (0.38) | BAZ2BLMNAALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL27793413 | 0.68 | BCHE (0.35) | BAZ2BLMNAALDH1A1BCHE | |
| SCHEMBL27701994 | 0.67 | BAZ2B (0.44) | BAZ2BLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6266520 | 0.67 | BAZ2B (0.44) | BAZ2BLMNAALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL21241213 | 0.66 | BAZ2B (0.43) | BAZ2BLMNAALDH1A1SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619698-B | Pyrrolidin derivatives and the purposes as complement pathway regulator thereof | 诺华股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104619698-A | Pyrrolidine derivatives and their use as complement pathway modulators | NOVARTIS AG | 2015-05-13 | — | — | CN | disclosed |