Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124577 | 0.95 | KMT2A (0.59) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL6753757 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL28792148 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL28048838 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL17433560 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL17433632 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL17433663 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL17433641 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL31439645 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL28048841 | 0.93 | KMT2A (0.57) | KMT2AMEN1NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829536-A | Antitumor activity phenyl pyrazole carboxylic acid compound and synthesis method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-08-12 | — | — | CN | claimed |
| CN-104803934-A | Phenyl isoxazole carboxylic acid type compound with antitumor activity as well as synthesis method and application thereof | UNIV SHAANXI SCIENCE & TECH | 2015-07-29 | — | — | CN | claimed |
| CN-104829536-A | Antitumor activity phenyl pyrazole carboxylic acid compound and synthesis method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-08-12 | — | — | CN | disclosed |
| CN-104803934-A | Phenyl isoxazole carboxylic acid type compound with antitumor activity as well as synthesis method and application thereof | UNIV SHAANXI SCIENCE & TECH | 2015-07-29 | — | — | CN | disclosed |