Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2694117 | 0.99 | L3MBTL1 (0.59) | L3MBTL1CREBBPFYNALKMAPK1 | |
| SCHEMBL2691700 | 0.83 | L3MBTL1 (0.40) | L3MBTL1CREBBPFYNALKMAPK1 | |
| Hydrochloric Acid SCHEMBL2692843 | 0.81 | L3MBTL1 (0.39) | L3MBTL1CREBBPFYNALKMAPK1 | |
| SCHEMBL27870423 | 0.77 | MAPK1 (0.42) | MAPK1KDM5B | |
| SCHEMBL28018702 | 0.77 | MAPK1 (0.34) | L3MBTL1MAPK1KDM5BPDK2 | |
| SCHEMBL27853688 | 0.76 | KIT (0.44) | MAPK1KDM5BPDK2 | |
| Hydrochloric Acid SCHEMBL2694026 | 0.76 | MAPK1 (0.34) | MAPK1KDM5BPDK2 | |
| Hydrochloric Acid SCHEMBL2692352 | 0.76 | MAPK1 (0.41) | MAPK1KDM5B | |
| SCHEMBL18803541 | 0.75 | MKNK1 (0.71) | L3MBTL1MAPK1MKNK1DYRK1BMKNK2 | |
| SCHEMBL15367198 | 0.74 | MAPK1 (0.46) | MAPK1KDM5BPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710420-B | Azabicyclic formula compound or its salt, containing its medicine, compositions and application | 大鹏药品工业株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-102471335-B | Azanebicyclic compound or salt thereof | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-104710420-A | Azabicyclo compound and salt thereof, medication and composition containing same, and application thereof | TAIHO PHARMACEUTICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |