Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801449 | 0.86 | AKR1C3 (0.48) | MAOBHTR2ACREBBPAKR1C3AKR1C2 | |
| SCHEMBL7160525 | 0.82 | CREBBP (0.61) | CREBBPTDP1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL8160004 | 0.82 | MAOB (0.52) | MAOBMAOAHTR2ACYP2B6MDH1 | |
| SCHEMBL15273702 | 0.82 | MAOA (0.45) | MAOBMAOAHTR2ACYP2B6MDH1 | |
| SCHEMBL4640374 | 0.82 | MAOA (0.45) | MAOBMAOAHTR2ACYP2B6MDH1 | |
| SCHEMBL14027049 | 0.82 | HPGD (0.50) | MAOBMAOAHTR2ACYP2B6MDH1 | |
| SCHEMBL12799701 | 0.81 | MAOB (0.63) | MAOBCYP2B6PDE4BMEN1ALDH1A1 | |
| SCHEMBL8481868 | 0.81 | CREBBP (0.47) | CREBBPAKR1C3AKR1C2TDP1HDAC1 | |
| SCHEMBL2804548 | 0.80 | PDE4B (0.40) | MAOBHTR2ACREBBPCYP2B6AKR1C3 | |
| SCHEMBL14648692 | 0.80 | KDM4E (0.50) | MAOBMAOACYP2B6MDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105617-A1 | C-Terminal Attachment of Two Chemical Groups to Peptides | NOVO NORDISK HEALTH CARE AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100105617-A1 | C-Terminal Attachment of Two Chemical Groups to Peptides | NOVO NORDISK HEALTH CARE AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100105617-A1 | C-Terminal Attachment of Two Chemical Groups to Peptides | NOVO NORDISK HEALTH CARE AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2121725-A1 | C-TERMINAL ATTACHMENT OF TWO CHEMICAL GROUPS TO PEPTIDES | Novo Nordisk Health Care AG (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008098958-A1 | C-TERMINAL ATTACHMENT OF TWO CHEMICAL GROUPS TO PEPTIDES | NOVO NORDISK HEALTH CARE AG (DK) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008098958-A1 | C-TERMINAL ATTACHMENT OF TWO CHEMICAL GROUPS TO PEPTIDES | NOVO NORDISK HEALTH CARE AG (DK) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105617-A1 | C-Terminal Attachment of Two Chemical Groups to Peptides | PTMS, DNPEP, VIP | MAOB 1932/4885MAOA 2137/4885HTR2A 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.