Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.60 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.58 |
| ▸ | RARB | P10826 | 7/20 | 0.56 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | RARA | P10276 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015889 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| SCHEMBL28019371 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| SCHEMBL28131071 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| SCHEMBL28019373 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| SCHEMBL28019900 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| SCHEMBL28019889 | 1.00 | PLK1 (0.60) | PLK1PLK3RARBKAT8PPARA | |
| Heptane SCHEMBL28015335 | 0.88 | ALDH1A1 (0.50) | PLK1KAT8PPARAMEN1ALDH1A1 | |
| Octane SCHEMBL28201125 | 0.88 | ALDH1A1 (0.50) | PLK1KAT8PPARAMEN1ALDH1A1 | |
| Dodecane SCHEMBL27541220 | 0.88 | ALDH1A1 (0.50) | PLK1KAT8PPARAMEN1ALDH1A1 | |
| SCHEMBL27676199 | 0.88 | ALDH1A1 (0.50) | PLK1KAT8PPARAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715669-A | Azeotropic like composition containing 2-chloro-1,3,3,3-tetrafluoropropene and 1-chloro-3,3,3-trifluoropropene | 中央硝子株式会社 | 2017-05-24 | — | — | CN | disclosed |
| CN-104675460-B | Method For Converting Thermal Energy Into Mechanical Energy, Organic Rankine Cycle Device, And Method For Replacing Working Fluid | 中央硝子株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-105408442-A | Heat transmission method and high-temperature heat pump device | CENTRAL GLASS CO LTD | 2016-03-16 | — | — | CN | disclosed |
| CN-104675460-A | Method For Converting Thermal Energy Into Mechanical Energy, Organic Rankine Cycle Device, And Method For Replacing Working Fluid | CENTRAL GLASS CO LTD | 2015-06-03 | — | — | CN | disclosed |