SCHEMBL28019388

SCHEMBL28019388

C=CC(=O)OCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 1/20 0.47
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762927 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28074197 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20787722 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14128872 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27660095 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28356458 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9189573 1.00 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12200005 0.98 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10051588 0.95 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29429551 0.94 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929066-A A kind of UV-cured resin, preparation method, coating 上海飞凯光电材料股份有限公司 2019-06-25 CN claimed
CN-106632886-A Polymer as well as preparation method and application thereof 清华大学 2017-05-10 CN claimed
CN-103665280-B A kind of multi-functional fluorine-containing microballoon and preparation method and application 中科院广州化学有限公司 2016-09-07 CN claimed
CN-104845521-A UV curing coating, wear-resistant and antifouling coating layer and mobile phone protection film containing wear-resistant and antifouling coating layer ZHANGJIAGANG KANGDE XIN PHOTOELECTRIC MATERIAL CO LTD 2015-08-19 CN claimed
CN-109517204-A A kind of superslide anti-biotic material and preparation method thereof and superslide anti-microbial catheter 威高集团有限公司 2019-03-26 CN disclosed
CN-107964070-A Water-soluble polymer and its application 清华大学 2018-04-27 CN disclosed
CN-106497183-A A kind of low rainbow line oil-stain-preventing cured film 江苏怡丽科姆新材料股份有限公司 2017-03-15 CN disclosed
CN-105648770-A Method for preparing super-hydrophobic surfaces 广州拜费尔空气净化材料有限公司 2016-06-08 CN disclosed
CN-104845521-A UV curing coating, wear-resistant and antifouling coating layer and mobile phone protection film containing wear-resistant and antifouling coating layer ZHANGJIAGANG KANGDE XIN PHOTOELECTRIC MATERIAL CO LTD 2015-08-19 CN disclosed