SCHEMBL12200005

SCHEMBL12200005

C=CC(=O)OCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.49
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.38
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20787722 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9189573 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL27660095 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28074197 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7762927 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28356458 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28019388 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14128872 0.98 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13613364 0.95 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16754222 0.94 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-07-15 US claimed
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-04-03 US claimed
WO-2023153586-A1 NOVEL META-POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (META-POSS) COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION COMPRISING META-POSS COMPOUND PRODUCED THEREBY 주식회사 파이오셀 2023-08-17 WO claimed
CN-106243856-B A kind of normal temperature solidifying fluorine-carbon dumb light finish and preparation method 巨化集团技术中心 2019-10-25 CN claimed
CN-107141375-B Norborneol alkenes ternary polymerization catalyst, preparation method and method for ternary polymerization 宁波工程学院 2019-06-11 CN claimed
CN-109810570-A Inorganic nano material prints ink and its preparation method and application TCL集团股份有限公司 2019-05-28 CN claimed
CN-107587120-B A kind of preparation method of the high insulating nano protective coating with modulated structure 江苏菲沃泰纳米科技有限公司 2018-12-18 CN claimed
CN-108425104-A A kind of coating production using sulfhydryl compound as transition zone 江苏菲沃泰纳米科技有限公司 2018-08-21 CN claimed
CN-107964071-A Aqueous dispersion polymers and its application 清华大学 2018-04-27 CN claimed
CN-107964070-A Water-soluble polymer and its application 清华大学 2018-04-27 CN claimed
CN-104558458-B A kind of fluorine silicon resin, preparation method and applications 山东三生新材料科技有限公司 2017-07-04 CN claimed
CN-106632886-A Polymer as well as preparation method and application thereof 清华大学 2017-05-10 CN claimed
CN-106243856-A A kind of normal temperature solidifying fluorine-carbon dumb light finish and preparation method 巨化集团技术中心 2016-12-21 CN claimed
CN-104452453-B A kind of speciality paper water base water and oil repellent agent and preparation method thereof 浙江恒达新材料股份有限公司 2016-08-24 CN claimed
CN-105369624-A Fluorine-containing finishing agent for hydrophobic and oleophobic fabric and preparation method of fluorine-containing finishing agent SUZHOU MAITASI CHIP TECH CO LTD 2016-03-02 CN claimed
CN-105254803-A Method for preparing fluorine-containing hydrophobic and oileophobic textile finishing agent UNIV NANTONG 2016-01-20 CN claimed
CN-105239397-A Fluorine-containing hydrophobic and oleophobic textile finishing agent UNIV NANTONG 2016-01-13 CN claimed
CN-104558458-A Fluoro-siloxane resin, preparation method and application thereof SHANDONG SANSHENG NEW MATERIAL TECHNOLOGY CO LTD 2015-04-29 CN claimed
CN-104452453-A Water-based waterproof oil-proof agent for special paper, and preparation method thereof ZHEJIANG HENGDA PAPER CO LTD 2015-03-25 CN claimed
CN-102766234-B Low-foam soap-free organic fluorine emulsion and preparation method thereof GUANGZHOU HUAYU CHEMICAL CO LTD 2015-02-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, OSTC TSHR 3556/4885ALDH1A1 4639/4885CYP3A4 1856/4885
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, SOST TSHR 3789/4885ALDH1A1 4652/4885CYP3A4 1898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.