Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.44 |
| ▸ | RET | P07949 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490382 | 0.78 | AURKA (0.39) | BRAFTNNI3KCHEK1AURKA | |
| SCHEMBL29538720 | 0.78 | AURKA (0.39) | BRAFTNNI3KCHEK1AURKA | |
| SCHEMBL6424611 | 0.75 | TRPA1 (0.45) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL30589329 | 0.75 | TRPA1 (0.45) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL23885471 | 0.73 | BRAF (0.39) | BRAFTNNI3K | |
| SCHEMBL30052556 | 0.73 | BRAF (0.39) | BRAFTNNI3K | |
| SCHEMBL22524176 | 0.71 | RET (0.40) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL30248822 | 0.71 | RET (0.40) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL25449356 | 0.71 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL21481681 | 0.71 | HTT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837832-A | GDF-8 inhibitors | RIGEL PHARMACEUTICALS INC | 2015-08-12 | — | — | CN | disclosed |