Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623883 | 0.78 | POLB (0.56) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL5094634 | 0.77 | KDM4E (0.67) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL6564351 | 0.75 | POLB (0.62) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL29419378 | 0.75 | POLB (0.62) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL29433500 | 0.75 | POLB (0.62) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL6118965 | 0.75 | POLB (0.62) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL12647390 | 0.75 | MEN1 (0.51) | POLBL3MBTL1KDM4EGAAMAPT | |
| SCHEMBL1054521 | 0.75 | POLB (0.53) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL29569200 | 0.75 | POLB (0.56) | POLBHCAR2L3MBTL1KDM4EHTT | |
| SCHEMBL27682219 | 0.75 | POLB (0.56) | POLBHCAR2L3MBTL1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073744-B | Novel heterocyclic compounds as bromine structural domain inhibitor | ZENITH EPIGENETICS CORP. (CA) | 2019-11-08 | — | — | CN | disclosed |
| CN-105073744-A | Novel heterocyclic compounds as bromodomain inhibitors | RVX THERAPEUTICS INC | 2015-11-18 | — | — | CN | disclosed |