SCHEMBL28019541

SCHEMBL28019541

OB(O)c1cc(-c2ccncc2)ccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.50
PIK3CA P42336 1/20 0.49
IMPDH2 P12268 1/20 0.48
PRKCI P41743 1/20 0.45
MKNK1 Q9BUB5 1/20 0.43
IKBKB O14920 2/20 0.42
CHUK O15111 1/20 0.42
IKBKE Q14164 1/20 0.42
PKMYT1 Q99640 1/20 0.42
PDK2 Q15119 1/20 0.42
MGLL Q99685 2/20 0.42
QDPR P09417 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
KIF11 P52732 1/20 0.41
CDC7 O00311 1/20 0.41
ROCK2 O75116 1/20 0.41
MAP4K4 O95819 1/20 0.41
PRKACA P17612 1/20 0.41
CDK2 P24941 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12551788 0.89 MGLL (0.50) PDK2MGLLCA1CA2KDM4E
SCHEMBL28019022 0.84 CYP11B1 (0.50) PIK3CAMKNK1PDK2ROCK2MAP4K4
SCHEMBL23152013 0.78 NOTUM (0.44) NOTUMIMPDH2PRKCIPRKACACDK2
SCHEMBL13682563 0.78 NOTUM (0.62) NOTUMPIK3CAIMPDH2PRKCIMKNK1
SCHEMBL9974913 0.76 NOTUM (0.71) NOTUMPIK3CAIMPDH2PRKCIMKNK1
SCHEMBL9974920 0.76 NOTUM (0.71) NOTUMPIK3CAIMPDH2PRKCIMKNK1
Boric Acid SCHEMBL31391090 0.75 NOTUM (0.79) NOTUMPRKCIMKNK1MGLLCA1
SCHEMBL28464178 0.75 RPS6KA3 (0.46) NOTUMMGLLCA1CA2PRKACA
SCHEMBL19533220 0.75 NOTUM (0.58) NOTUMPIK3CAIMPDH2PRKCIMKNK1
SCHEMBL31576793 0.74 MGLL (0.50) MGLLCA1CA2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744347-A Dianthracene compounds containing pyridyl at terminals and application thereof JIANGSU HECHENG ADVANCED MATERIALS CO LTD 2015-07-01 CN disclosed