Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310283 | 0.86 | CA12 (0.45) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL29122407 | 0.84 | CA12 (0.46) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL22091994 | 0.84 | CA12 (0.46) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL5742303 | 0.84 | CA12 (0.46) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL17327490 | 0.81 | FKBP1A (0.46) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL19075596 | 0.80 | FKBP1A (0.43) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL28451036 | 0.80 | FKBP1A (0.43) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL30725353 | 0.79 | CA12 (0.40) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL5635061 | 0.77 | CA12 (0.36) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL1150296 | 0.77 | CA12 (0.44) | CA12CA1CA2CA9FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414190-B | Inhibitors of NF-kB | PROFECTUS BIOSCIENCES INC | 2015-06-03 | — | — | CN | claimed |
| CN-102414190-B | Inhibitors of NF-kB | PROFECTUS BIOSCIENCES INC | 2015-06-03 | — | — | CN | disclosed |