Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020288 | 0.85 | MAPK8 (0.42) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL28820177 | 0.84 | TAAR1 (0.39) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL30721403 | 0.84 | LOX (0.40) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL12015 | 0.80 | CCR1 (0.41) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL29520064 | 0.80 | CCR1 (0.41) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL28820124 | 0.80 | RXRA (0.41) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL16002427 | 0.79 | TSHR (0.42) | TSHRRXRAGRIN1GRIN2BALDH1A1 | |
| SCHEMBL27990718 | 0.78 | CCR1 (0.40) | RXRAGRIN1GRIN2BLOXLOXL2 | |
| SCHEMBL6223037 | 0.78 | TSHR (0.38) | TSHRRXRAGRIN1GRIN2BNOS2 | |
| SCHEMBL14880376 | 0.78 | SCN9A (0.44) | TSHRRXRAGRIN1GRIN2BNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |