Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.47 |
| ▸ | LCK | P06239 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115305 | 0.84 | HSD17B10 (0.43) | NLRP3MAPK1EPHX2HSD17B10TSHR | |
| SCHEMBL28505718 | 0.83 | ATR (0.40) | NLRP3LCKHSD17B10TSHRPPARG | |
| SCHEMBL24574915 | 0.81 | LCK (0.60) | NLRP3LCKHSD17B10TSHRALDH1A1 | |
| SCHEMBL6802645 | 0.80 | HSD17B10 (0.46) | EPHX2HSD17B10PPARGKDM4EGAA | |
| SCHEMBL2997971 | 0.77 | LCK (0.44) | NLRP3LCKMAPK1HSD17B10TSHR | |
| SCHEMBL2997409 | 0.76 | LCK (0.52) | NLRP3LCKMAPK1HSD17B10TSHR | |
| SCHEMBL28975896 | 0.76 | MEN1 (0.42) | NLRP3MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL22941226 | 0.75 | NLRP3 (0.50) | NLRP3LCKHSD17B10TSHR | |
| SCHEMBL8787245 | 0.75 | KDM4E (0.46) | EPHX2KDM4EKMT2A | |
| SCHEMBL2352982 | 0.75 | LCK (0.51) | NLRP3LCKMAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485273-A | N- (heterocyclyl and heterocyclylalkyl) -3-benzylpyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2022-12-16 | — | — | CN | disclosed |
| CN-104837858-A | Ketoamide immunoproteasome inhibitors | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |