SCHEMBL28020517

SCHEMBL28020517

CC1(C)CO1.Cc1ccccc1C(=O)OCC(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
TSHR P16473 2/20 0.62
ADRB2 P07550 2/20 0.53
ADRB1 P08588 2/20 0.53
ADRB3 P13945 2/20 0.53
MAPT P10636 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TP53 P04637 1/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ADRA1D P25100 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
KDM4E B2RXH2 2/20 0.43
HTT P42858 2/20 0.43
NPC1 O15118 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6057357 0.88 ALDH1A1 (0.79) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL28020077 0.82 ALDH1A1 (0.61) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL28020503 0.81 KDM4E (0.49) ALDH1A1ADRB2ADRB1ADRB3MAPT
SCHEMBL28020526 0.81 ALDH1A1 (0.59) ALDH1A1TSHRADRB2ADRB1ADRB3
Toluic Acid SCHEMBL27303668 0.80 ALDH1A1 (0.75) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL28020139 0.80 TSHR (0.63) ALDH1A1TSHRMAPTTP53ADRA1D
SCHEMBL29387332 0.78 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL42787 0.78 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL8144263 0.78 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL17797889 0.78 ALDH1A1 (0.62) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829756-A Solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed