Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 7/20 | 0.64 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TLR2 | O60603 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | FABP4 | P15090 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596848 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28598663 | 0.98 | GPR84 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28261360 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28429423 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28262571 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL27802249 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28873581 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28429930 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL31249636 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL28262553 | 0.96 | GPR84 (0.71) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113201511-B | (R) -5-carbonyl decanoate (ester) reductase mutant and application thereof in preparation of (R) -gamma/delta-lactone | 华东理工大学 | 2022-08-30 | — | — | CN | claimed |
| CN-104651425-B | A kind of method of living things catalysis synthesizing optical active al lactone | 苏州百福安酶技术有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-104651425-A | Method for biological catalyzed synthesis of optically active alkyl lactone | SUZHOU BAIFU AN ENZYME TECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-113201511-B | (R) -5-carbonyl decanoate (ester) reductase mutant and application thereof in preparation of (R) -gamma/delta-lactone | 华东理工大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109797140-B | Carbonyl reductase mutant, encoding gene, recombinant vector, expression transformant and application of carbonyl reductase mutant in preparation of (R) -alkyl lactone | 苏州百福安酶技术有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-113278599-A | Saccharomyces cerevisiae carbonyl reductase and application thereof in preparation of optically active alkyl lactone | 华东理工大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-113201511-A | (R) -5-carbonyl decanoate (ester) reductase mutant and application thereof in preparation of (R) -gamma/delta-lactone | 华东理工大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-107142251-B | Serratia carbonyl reductase and application thereof in preparation of optically active alkyl lactone | 苏州百福安酶技术有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-109797140-A | Carbonyl reduction enzyme mutant, encoding gene, recombinant vector and expression transformant and its in the application of preparation (R)-alkyl lactone | 苏州百福安酶技术有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-104651425-B | A kind of method of living things catalysis synthesizing optical active al lactone | 苏州百福安酶技术有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107142251-A | Serratieae carbonyl reductase and its application in optical activity alkyl lactone is prepared | 苏州百福安酶技术有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-104651425-A | Method for biological catalyzed synthesis of optically active alkyl lactone | SUZHOU BAIFU AN ENZYME TECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104651425-A | Method for biological catalyzed synthesis of optically active alkyl lactone | SUZHOU BAIFU AN ENZYME TECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | disclosed |