Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.36 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27995148 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL7800329 | 0.80 | TSHR (0.56) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL20312338 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL27657136 | 0.69 | CYP3A4 (0.39) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL12270752 | 0.68 | KDM4E (0.81) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL27830612 | 0.68 | ALDH1A1 (0.43) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL907509 | 0.68 | TSHR (0.40) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL28994183 | 0.67 | TSHR (0.38) | ALDH1A1CYP1A2CYP3A4TSHRKMT2A | |
| Ether SCHEMBL28632893 | 0.67 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 | |
| SCHEMBL28994680 | 0.66 | TSHR (0.39) | ALDH1A1CYP1A2TDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977188-B | GNRH (gonadotropin-releasing hormone) peptide variants | MEDICAL RES COUNCIL | 2015-07-15 | — | — | CN | disclosed |