SCHEMBL28021247

SCHEMBL28021247

NS(=O)(=O)C1C=CC=CC1(F)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.34
MAOA P21397 4/20 0.34
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA5A P35218 2/20 0.31
CA9 Q16790 2/20 0.31
CA12 O43570 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA7 P43166 1/20 0.31
PLA2G7 Q13093 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8695942 0.77 CA1 (0.32) CA1CA2CA5ACA9CA12
SCHEMBL17609450 0.75 MAOB (0.33) MAOBMAOACA1CA2CA5A
SCHEMBL7364601 0.74
SCHEMBL15346092 0.73 KDM1A (0.30) MAOBMAOA
SCHEMBL28014648 0.72 MAOB (0.36) MAOBMAOA
SCHEMBL1143476 0.71 KDM4E (0.31)
SCHEMBL15973215 0.68
SCHEMBL7406879 0.68
SCHEMBL4183576 0.68 CA2 (0.37) MAOBMAOACA1CA2CA5A
SCHEMBL9246385 0.67 RXFP1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102958540-B Containing the combination of 2,3-glyoxalidine also [1, the 2-C] quinazoline replaced BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-09-02 CN disclosed