Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196761 | 0.81 | KDM5A (0.41) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL7294353 | 0.81 | HSP90AB1 (0.62) | HSP90AB1POLBHTTCA12CA1 | |
| SCHEMBL12911463 | 0.78 | RXFP1 (0.43) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28043705 | 0.74 | POLB (0.65) | HSP90AB1POLBHTTCA9ALDH1A1 | |
| Propionaldehyde SCHEMBL28055637 | 0.73 | HSP90AB1 (0.83) | HSP90AB1POLBHTTCA12CA1 | |
| SCHEMBL29457585 | 0.73 | HSP90AB1 (1.00) | HSP90AB1POLBHTTCA12CA1 | |
| SCHEMBL481085 | 0.73 | HSP90AB1 (1.00) | HSP90AB1POLBHTTCA12CA1 | |
| SCHEMBL4706474 | 0.73 | HSP90AB1 (1.00) | HSP90AB1POLBHTTCA12CA1 | |
| SCHEMBL5464068 | 0.72 | CYP3A4 (0.53) | POLBHTTKDM5AALDH1A1CYP3A4 | |
| SCHEMBL7253586 | 0.72 | HSP90AB1 (0.69) | HSP90AB1POLBHTTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876828-A | Method for synthesizing synephrine, its hydrochloride and tartrate | LI YUSHAN | 2015-09-02 | — | — | CN | disclosed |