SCHEMBL28043705

SCHEMBL28043705

CCC(=O)c1ccc(NC=O)cc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.65
HSP90AB1 P08238 1/20 0.57
ALDH1A1 P00352 4/20 0.46
HMGCR P04035 1/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
PAK4 O96013 1/20 0.42
ABL1 P00519 1/20 0.42
NTRK1 P04629 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42
IGF1R P08069 1/20 0.42
MET P08581 1/20 0.42
PDGFRB P09619 1/20 0.42
PIM1 P11309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635128 0.80 KMT2A (0.56) POLBALDH1A1RAB9ANPC1CA9
SCHEMBL11235452 0.79 POLB (1.00) POLBHSP90AB1ALDH1A1CHEK1AURKA
SCHEMBL5461908 0.79 SMN1; SMN2 (0.64) POLBALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL27996243 0.76 POLB (0.63) POLBHSP90AB1ALDH1A1HMGCRCHEK1
SCHEMBL28021311 0.74 HSP90AB1 (0.57) POLBHSP90AB1ALDH1A1HMGCRHTT
SCHEMBL17570995 0.74 MAPT (0.48) ALDH1A1RAB9ANPC1HTTSMN1; SMN2
Propionaldehyde SCHEMBL28055637 0.73 HSP90AB1 (0.83) POLBHSP90AB1ALDH1A1RAB9ANPC1
SCHEMBL29457585 0.73 HSP90AB1 (1.00) POLBHSP90AB1ALDH1A1HMGCRRAB9A
SCHEMBL481085 0.73 HSP90AB1 (1.00) POLBHSP90AB1ALDH1A1HMGCRRAB9A
SCHEMBL4706474 0.73 HSP90AB1 (1.00) POLBHSP90AB1ALDH1A1HMGCRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105154235-B A kind of cigarette Chinese photinia fragrance, preparation method and applications 河南中烟工业有限责任公司 2019-03-08 CN disclosed
CN-105154235-A Cigarette Chinese photinia perfume, and preparation method and application thereof CHINA TOBACCO HENAN IND CO LTD 2015-12-16 CN disclosed