Methane

Methane

SCHEMBL28021409

C.Fc1ccc(F)c(F)c1

nearest known ligand 0.52

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ALDH1A1 P00352 1/20 0.52
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
NFE2L2 Q16236 7/20 0.44
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
IDO1 P14902 2/20 0.41
AGXT P21549 2/20 0.41
KDM1A O60341 2/20 0.39
KDM1B Q8NB78 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28949904 1.00 CA3 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL180042 0.97
SCHEMBL29352228 0.97
Bromide SCHEMBL1682049 0.93 CA3 (0.52) CA3CA6CA5ACA9CA14
Hydrochloric Acid SCHEMBL1682129 0.93 CA3 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL27856362 0.93 CA3 (0.52) CA3CA6CA5ACA9CA14
Ethylene SCHEMBL28105896 0.90 CA3 (0.50) CA3CA6CA5ACA9CA14
Nitrogen SCHEMBL28393401 0.90 CA3 (0.50) CA3CA6CA5ACA9CA14
Bromide SCHEMBL27873066 0.90 CA3 (0.50) CA3CA6CA5ACA9CA14
Cyanide SCHEMBL27522786 0.88 CA3 (0.48) CA3CA6CA5ACA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744613-A Half-metallocene catalyst containing fluorobenzene amidine, preparation method and application thereof SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD 2015-07-01 CN disclosed