CA3

Carbonic anhydrase 3 · P07451 · CA3 on Sugi Atlas →

142,242 patent compounds predicted against CA3, 95,330 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Coumarin (SCHEMBL6252)	1.00	7/20
Benzthiazide (SCHEMBL26257)	0.42	7/20
SCHEMBL16810	0.42	5/20
Benzthiazide (SCHEMBL26258)	0.42	5/20
Benzenesulfonamide (SCHEMBL729)	1.00	4/20
Acetazolamide (SCHEMBL23219)	1.00	4/20
Acetazolamide (SCHEMBL40812)	0.97	4/20
SCHEMBL42927	0.87	4/20
SCHEMBL52075	0.52	4/20
Busulfan (SCHEMBL4373)	0.48	4/20
Improsulfan (SCHEMBL8954)	0.33	4/20
Busulfan (SCHEMBL45667)	0.31	4/20
Trientine (SCHEMBL15439)	1.00	3/20
Spermidine (SCHEMBL15618)	1.00	3/20
SCHEMBL15797	1.00	3/20
Caffeic Acid (SCHEMBL23358)	1.00	3/20
Caffeic Acid (SCHEMBL23359)	1.00	3/20
Methazolamide (SCHEMBL24686)	1.00	3/20
Methazolamide (SCHEMBL24687)	1.00	3/20
SCHEMBL26707	1.00	3/20

Clinical trials — most relevant to CA3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise	PHASE4	COMPLETED
Zonegran in the Treatment of Binge Eating Disorder Associated With Obesity	PHASE3	COMPLETED
Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy	PHASE2	RECRUITING
Acetazolamide for Treatment Resistant Schizophrenia	PHASE1/PHASE2	RECRUITING
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients	PHASE2	WITHDRAWN
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Trauma Patients	PHASE2	WITHDRAWN
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment	PHASE2	COMPLETED
The Etiology and Progression of Brain Tumors	nan	COMPLETED
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study	nan	COMPLETED
Making Mindfulness Matter© in Children With Epilepsy	nan	COMPLETED
Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers	nan	COMPLETED
Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers	nan	COMPLETED
Pediatric Epilepsy	nan	NOT_YET_RECRUITING
The Energetic Origin of Neurodegeneration in MS	nan	COMPLETED
Role of Concentration of Biomarkers S100B and NSE in Serum in Mild and Moderate Head Trauma	nan	UNKNOWN
Efficient Automated Localization of ECoG Electrodes in CT Images Via Shape Analysis	nan	COMPLETED
Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex	nan	UNKNOWN
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database	nan	RECRUITING
Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder	nan	COMPLETED
Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach	nan	RECRUITING
Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome	nan	UNKNOWN
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study	nan	RECRUITING
Predictors of Drug Resistant Epilepsy Among Pediatric Patients	nan	NOT_YET_RECRUITING
The Neuroprotective Effect of Dexmedetomidine Preserving Brain Functional Connectivity in Elderly Patients	nan	COMPLETED
Non-Invasive Seizure Localization in Patients With Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings	nan	COMPLETED
Focused Ultrasound Neuromodulation for Treatment of Temporal Lobe Epilepsy	nan	WITHDRAWN
Definition, Quantification, and Utility of Biomarkers of Repetitive Brain Injury in Predicting Concussion and Other Long-Term Injury Risks in Patients With Atrial Fibrillation (Concussion AF)	nan	COMPLETED
Human Epilepsy Genetics--Neuronal Migration Disorders Study	nan	RECRUITING
The Effect of TRA-8 on Ovarian Cancer Tissue	nan	COMPLETED
Calciotropic Effects After HCG Stimulation Test	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CA3 binder may also engage these)

Protein	Name	Similarity
P07450	—	1.000	P07450 →
Q5S1S4	—	1.000	Q5S1S4 →
Q3SZX4	—	1.000	Q3SZX4 →
P16015	—	1.000	P16015 →
Q9D6N1	—	1.000	Q9D6N1 →
P14141	—	0.999	P14141 →
CA13	Carbonic anhydrase 13	0.999	landscape →
P27139	—	0.997	P27139 →
P07630	—	0.996	P07630 →
Q9ERQ8	—	0.995	Q9ERQ8 →
CA7	Carbonic anhydrase 7	0.994	landscape →
P48282	—	0.994	P48282 →
CA2	Carbonic anhydrase 2	0.994	landscape →
P35217	—	0.992	P35217 →
P00920	—	0.991	P00920 →
P00921	—	0.991	P00921 →
Q8HY33	—	0.990	Q8HY33 →
P00916	—	0.990	P00916 →
Q8UWA5	—	0.989	Q8UWA5 →
P00919	—	0.989	P00919 →
P07452	—	0.989	P07452 →
Q1LZA1	—	0.989	Q1LZA1 →
P13634	—	0.988	P13634 →
Q92051	—	0.987	Q92051 →
Q7M316	—	0.985	Q7M316 →
P00922	—	0.985	P00922 →
CA1	Carbonic anhydrase 1	0.983	landscape →
Q7M317	—	0.983	Q7M317 →
B0BNN3	—	0.983	B0BNN3 →
P83299	—	0.982	P83299 →