Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 10/20 | 0.72 |
| ▸ | BRAF | P15056 | 4/20 | 0.56 |
| ▸ | ABL1 | P00519 | 6/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4103102 | 0.84 | KIT (1.00) | KITBRAFABL1CSF1RFGFR1 | |
| SCHEMBL29856181 | 0.84 | KIT (1.00) | KITBRAFABL1CSF1RFGFR1 | |
| SCHEMBL14318406 | 0.83 | KIT (0.77) | KITBRAFABL1EGFRCSF1R | |
| SCHEMBL29562197 | 0.83 | KIT (0.77) | KITBRAFABL1EGFRCSF1R | |
| SCHEMBL24503732 | 0.83 | KIT (0.85) | KITBRAFABL1EGFRCSF1R | |
| SCHEMBL18323290 | 0.83 | KIT (0.85) | KITBRAFABL1EGFRCSF1R | |
| SCHEMBL31620840 | 0.82 | KIT (0.76) | KITABL1FGFR1 | |
| SCHEMBL16755327 | 0.82 | KIT (0.81) | KITBRAFABL1CSF1RFGFR1 | |
| SCHEMBL30080773 | 0.82 | KIT (0.93) | KITBRAFABL1EGFRCSF1R | |
| SCHEMBL17936186 | 0.82 | KIT (0.93) | KITBRAFABL1EGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797581-A | HETEROARYL ALKYNE COMPOUND AND APPLICATION THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-07-22 | — | — | CN | disclosed |