Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.76 |
| ▸ | ABL1 | P00519 | 14/20 | 0.65 |
| ▸ | ABL2 | P42684 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620766 | 0.87 | KIT (1.00) | KITABL1FGFR1CYP2C9PDGFRA | |
| SCHEMBL31620756 | 0.85 | ABL1 (0.78) | KITABL1RETFGFR1CYP2C9 | |
| SCHEMBL21730542 | 0.84 | KIT (0.85) | KITABL1ABL2RETFGFR1 | |
| SCHEMBL29562844 | 0.82 | SRC (0.62) | KITABL1FGFR1PDGFRA | |
| SCHEMBL28021485 | 0.82 | KIT (0.72) | KITABL1FGFR1 | |
| SCHEMBL31620876 | 0.82 | KIT (0.58) | KITABL1ABL2RET | |
| SCHEMBL29758813 | 0.81 | ABL1 (0.78) | KITABL1ABL2RETFGFR1 | |
| SCHEMBL29675313 | 0.80 | KIT (0.83) | KITABL1RETFGFR1CYP2C9 | |
| SCHEMBL24626341 | 0.79 | KIT (0.79) | KITABL1RETFGFR1CYP2C9 | |
| SCHEMBL24626254 | 0.79 | KIT (0.72) | KITABL1RETFGFR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | disclosed |