Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022399 | 0.77 | APOBEC3G (0.67) | APOBEC3GTDP1ALDH1A1HSD17B10HSD11B1 | |
| SCHEMBL4613713 | 0.77 | APOBEC3G (0.54) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 | |
| SCHEMBL5533428 | 0.77 | APOBEC3G (0.73) | APOBEC3GTDP1ALDH1A1ESR1HSD17B10 | |
| SCHEMBL121410 | 0.77 | APOBEC3G (1.00) | APOBEC3GTDP1ALDH1A1ESR1HSD17B10 | |
| SCHEMBL4569289 | 0.76 | ADAMTS4 (0.53) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 | |
| Hydrochloric Acid SCHEMBL28541249 | 0.76 | APOBEC3G (0.52) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 | |
| SCHEMBL3283058 | 0.74 | APOBEC3G (0.50) | APOBEC3GTDP1ESR1HSD11B1KMT2A | |
| SCHEMBL27378456 | 0.74 | APOBEC3G (0.50) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 | |
| SCHEMBL5284140 | 0.74 | APOBEC3G (0.50) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 | |
| SCHEMBL27953448 | 0.74 | APOBEC3G (0.50) | APOBEC3GTDP1ALDH1A1ESR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797561-A | fused bicyclic Sulfamoyl derivatives and their use as medicaments for the treatment of hepatitis B | JANSSEN R & AMP | 2015-07-22 | — | — | CN | disclosed |