Fluoride

Fluoride

SCHEMBL28021589

C=CC(=O)N(C)CCCC.F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.45
ZDHHC2 Q9UIJ5 2/20 0.45
EPHX2 P34913 5/20 0.40
TSHR P16473 4/20 0.39
HPGD P15428 2/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
ALDH1A1 P00352 2/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
FAAH O00519 1/20 0.35
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
ESR1 P03372 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL325417 0.98 ZDHHC20 (0.46) ZDHHC20ZDHHC2EPHX2TSHRHPGD
Trimethylammonium SCHEMBL28166566 0.96 ZDHHC20 (0.45) ZDHHC20ZDHHC2EPHX2TSHRHPGD
Ammonia Solution, Strong SCHEMBL27592102 0.96 ZDHHC20 (0.45) ZDHHC20ZDHHC2EPHX2TSHRHPGD
Dimethylamine SCHEMBL27558837 0.92 ZDHHC20 (0.42) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL15233356 0.92 ZDHHC20 (0.53) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL2874278 0.90 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL7632696 0.90 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL6515558 0.90 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL12200640 0.90 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2TSHRHPGD
SCHEMBL4083031 0.90 ZDHHC20 (0.56) ZDHHC20ZDHHC2EPHX2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105263978-B Salt tolerant star-like macromolecules ATRP解决方案公司 2018-04-17 CN disclosed
CN-105263978-A Salt-tolerant star macromolecules ATRP SOLUTIONS INC 2016-01-20 CN disclosed
CN-104704067-A Slippery self-lubricating polymer surfaces HARVARD COLLEGE 2015-06-10 CN disclosed