Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.34 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5580294 | 0.89 | KCNH2 (0.37) | KMT2AMAPTKCNH2GPR84PPARG | |
| Acetic Acid SCHEMBL11224897 | 0.89 | KCNH2 (0.37) | KMT2AMAPTKCNH2GPR84PPARG | |
| SCHEMBL1138502 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL10431497 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL107098 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL11250645 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL2949529 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL750715 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL21049558 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 | |
| SCHEMBL9814327 | 0.86 | GNAI3 (0.37) | KMT2AALDH1A1MEN1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105749702-A | Method and device for treating benzene series VOCs in organic exhaust gas by adopting foam absorption method | 暨南大学 | 2016-07-13 | — | — | CN | claimed |
| CN-105688638-A | Method and device for treating sulfur-containing waste gas by utilizing foam absorption method | 暨南大学 | 2016-06-22 | — | — | CN | claimed |
| CN-105749702-A | Method and device for treating benzene series VOCs in organic exhaust gas by adopting foam absorption method | 暨南大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-105688638-A | Method and device for treating sulfur-containing waste gas by utilizing foam absorption method | 暨南大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-104841083-A | Dissolution-resistant foamite | XIAMEN ONGOING FIREFIGHTING TECHNOLOGY CO LTD | 2015-08-19 | — | — | CN | disclosed |