Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | SHBG | P04278 | 2/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433090 | 0.92 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL28716683 | 0.90 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL10723863 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| Acetic Acid SCHEMBL4651980 | 0.88 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| Bicarbonate SCHEMBL6684636 | 0.88 | CYP3A4 (0.65) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| Acetic Acid SCHEMBL2042107 | 0.88 | CYP3A4 (0.65) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL571703 | 0.88 | CYP3A4 (0.67) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL4747200 | 0.88 | CYP3A4 (0.67) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL2724646 | 0.88 | CYP3A4 (0.67) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA | |
| SCHEMBL25333984 | 0.88 | CYP3A4 (0.67) | SMN1; SMN2ALDH1A1CYP3A4SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292305-A | Pharmaceutical co-crystal of progesterone and formic acid derivative and application thereof | 国家卫生健康委科学技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-105085596-A | Preparation method of progesterone carboxylate | HUBEI ZHUXI RENFU PHARMACEUTICAL CO LTD | 2015-11-25 | — | — | CN | disclosed |
| CN-105085596-A | Preparation method of progesterone carboxylate | HUBEI ZHUXI RENFU PHARMACEUTICAL CO LTD | 2015-11-25 | — | — | CN | disclosed |