Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28021812 | 1.00 | — | — | |
| SCHEMBL28891499 | 0.85 | — | — | |
| SCHEMBL28184157 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL28853034 | 0.83 | ALDH1A1 (0.32) | — | |
| SCHEMBL7922490 | 0.72 | — | — | |
| SCHEMBL7625024 | 0.72 | — | — | |
| SCHEMBL5732382 | 0.70 | — | — | |
| SCHEMBL28128095 | 0.69 | — | — | |
| SCHEMBL28167857 | 0.67 | — | — | |
| SCHEMBL28137402 | 0.67 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103706397-B | Polymetallic oxygen cluster immobilized chiral catalyst, preparation method thereof and application thereof to chiral resolution and catalytic oxidation | UNIV JILIN | 2015-07-22 | — | — | CN | disclosed |