Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711947 | 0.88 | TSHR (0.51) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL4920806 | 0.83 | LMNA (0.49) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL5805479 | 0.81 | TSHR (0.57) | TSHRLMNAALDH1A1GLASMN1; SMN2 | |
| SCHEMBL11432478 | 0.81 | TP53 (0.51) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL4910205 | 0.81 | TP53 (0.47) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL9249496 | 0.81 | TSHR (0.53) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL3081849 | 0.81 | HCAR2 (0.47) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4953155 | 0.78 | TSHR (0.50) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL4922482 | 0.78 | NPC1 (0.46) | TSHRLMNAALDH1A1GLATP53 | |
| SCHEMBL11438696 | 0.78 | HPGD (0.48) | TSHRLMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788343-A | Ortho-substituted allyl carbamate compound and preparation method thereof | UNIV TONGJI | 2015-07-22 | — | — | CN | disclosed |