Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.83 |
| ▸ | LCK | P06239 | 10/20 | 0.83 |
| ▸ | TEK | Q02763 | 9/20 | 0.83 |
| ▸ | KDR | P35968 | 4/20 | 0.69 |
| ▸ | EGFR | P00533 | 3/20 | 0.69 |
| ▸ | FYN | P06241 | 2/20 | 0.69 |
| ▸ | LYN | P07948 | 2/20 | 0.69 |
| ▸ | CSK | P41240 | 2/20 | 0.69 |
| ▸ | BTK | Q06187 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | RGS12 | O14924 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28022481 | 0.91 | SRC (0.77) | SRCLCKTEKKDREGFR | |
| SCHEMBL6465227 | 0.91 | SRC (1.00) | SRCLCKTEKKDREGFR | |
| Hydrochloric Acid SCHEMBL6465660 | 0.90 | SRC (0.98) | SRCLCKTEKKDREGFR | |
| SCHEMBL16752225 | 0.86 | SRC (0.89) | SRCLCKTEKKDREGFR | |
| SCHEMBL6865210 | 0.85 | SRC (1.00) | SRCLCKTEKKDREGFR | |
| SCHEMBL14617844 | 0.85 | SRC (1.00) | SRCLCKTEKKDREGFR | |
| Hydrochloric Acid SCHEMBL6462081 | 0.85 | SRC (0.98) | SRCLCKTEKKDREGFR | |
| Tert-Butyl Formate SCHEMBL28307546 | 0.84 | SRC (0.70) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL7843774 | 0.84 | SRC (0.70) | SRCLCKTEKKDREGFR | |
| Tert-Butyl Formate SCHEMBL28022107 | 0.84 | LCK (0.71) | SRCLCKTEKKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854107-A | Pyrrolopyrimidine compounds as kinase inhibitors | PHARMACYCLICS INC | 2015-08-19 | — | — | CN | disclosed |