Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.70 |
| ▸ | LCK | P06239 | 9/20 | 0.70 |
| ▸ | TEK | Q02763 | 8/20 | 0.70 |
| ▸ | KDR | P35968 | 5/20 | 0.63 |
| ▸ | EGFR | P00533 | 3/20 | 0.63 |
| ▸ | FYN | P06241 | 2/20 | 0.63 |
| ▸ | LYN | P07948 | 2/20 | 0.63 |
| ▸ | CSK | P41240 | 2/20 | 0.63 |
| ▸ | BTK | Q06187 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RGS12 | O14924 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6877622 | 0.86 | SRC (0.78) | SRCLCKTEKKDREGFR | |
| SCHEMBL6462070 | 0.85 | SRC (0.78) | SRCLCKTEKKDREGFR | |
| SCHEMBL30054291 | 0.85 | SRC (0.78) | SRCLCKTEKKDREGFR | |
| Tert-Butyl Formate SCHEMBL28022044 | 0.84 | SRC (0.83) | SRCLCKTEKKDREGFR | |
| SCHEMBL6465227 | 0.83 | SRC (1.00) | SRCLCKTEKKDREGFR | |
| Hydrochloric Acid SCHEMBL6465660 | 0.83 | SRC (0.98) | SRCLCKTEKKDREGFR | |
| SCHEMBL30143837 | 0.82 | SRC (0.64) | SRCLCKTEKKDREGFR | |
| SCHEMBL15516942 | 0.82 | SRC (0.79) | SRCLCKTEKKDREGFR | |
| SCHEMBL13858297 | 0.82 | SRC (0.79) | SRCLCKTEKKDREGFR | |
| SCHEMBL7135493 | 0.82 | HCK (0.73) | SRCLCKTEKKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |