Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | RAD52 | P43351 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15358686 | 0.88 | ALDH1A1 (0.81) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL76629 | 0.84 | ALDH1A1 (0.96) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL30336487 | 0.82 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL160768 | 0.82 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL22653981 | 0.80 | AKR1C3 (0.49) | ALDH1A1POLBKDM4EHTTLMNA | |
| SCHEMBL6128549 | 0.79 | ALDH1A1 (0.68) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL156279 | 0.79 | MAPT (0.96) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL17264124 | 0.79 | ALDH1A1 (0.75) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL78364 | 0.79 | MAPT (1.00) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL18452907 | 0.79 | MAPT (0.69) | ALDH1A1POLBMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-104725356-A | Nitrogen heterocyclic derivatives and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-06-24 | — | — | CN | disclosed |