Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645106 | 0.82 | FAAH (0.56) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL2181000 | 0.79 | FAAH (0.64) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL27599940 | 0.78 | FAAH (0.52) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL12781907 | 0.78 | FAAH (0.59) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL526071 | 0.78 | FAAH (0.52) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL526735 | 0.78 | FAAH (0.65) | FAAHRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL14946891 | 0.77 | FAAH (0.48) | FAAHNPC1RAB9ANLRP3KMO | |
| SCHEMBL1907307 | 0.76 | FAAH (0.53) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL425371 | 0.76 | FAAH (0.60) | FAAHNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL18986536 | 0.75 | MAP4K4 (0.39) | FAAHPARP1MAP2K3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450089-B | Preparation method of 4-phenylimidazole | ZHANGJIAGANG XINYI CHEMICAL CO LTD | 2015-07-15 | — | — | CN | disclosed |