Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.66 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pteroic Acid SCHEMBL245982 | 0.99 | DHFR (0.67) | DHFRCA1CA2CA9KDM4E | |
| Pteroic Acid SCHEMBL27919717 | 0.98 | DHFR (0.66) | DHFRCA1CA2CA9KDM4E | |
| Pteroic Acid SCHEMBL16047869 | 0.98 | DHFR (0.66) | DHFRCA1CA2CA9KDM4E | |
| SCHEMBL28985427 | 0.91 | DHFR (0.80) | DHFRCA1CA2CA9 | |
| SCHEMBL13683833 | 0.91 | DHFR (0.63) | DHFRCA1CA2CA9 | |
| SCHEMBL12867919 | 0.90 | DHFR (0.65) | DHFRCA1CA2CA9KDM4E | |
| SCHEMBL20647289 | 0.90 | DHFR (0.62) | DHFRCA1CA2CA9 | |
| SCHEMBL14417311 | 0.89 | DHFR (0.81) | DHFRCA1CA2CA9 | |
| SCHEMBL20806703 | 0.88 | DHFR (0.60) | DHFRCA1CA2CA9KDM4E | |
| SCHEMBL19997525 | 0.88 | DHFR (0.60) | DHFRCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761553-A | Method for preparing pteroic acid | CHANGZHOU YIZE MEDICINE CHEMICAL SCIENCE & TECHNOLOGY CO LTD | 2015-07-08 | — | — | CN | claimed |
| CN-109734717-A | Pteroic acid novel crystal forms and preparation method thereof | 苏州华健瑞达医药技术有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-104761553-A | Method for preparing pteroic acid | CHANGZHOU YIZE MEDICINE CHEMICAL SCIENCE & TECHNOLOGY CO LTD | 2015-07-08 | — | — | CN | disclosed |