Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023132 | 0.86 | NPC1 (0.64) | CYP19A1MAOBNPC1RAB9ACASP3 | |
| SCHEMBL123187 | 0.76 | MAOB (0.68) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL29382160 | 0.74 | MAOB (1.00) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL107774 | 0.74 | MAOB (1.00) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL14129341 | 0.73 | MAOB (0.66) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL7294371 | 0.72 | MAOB (0.56) | CYP19A1MAOBRAB9AMAOAACHE | |
| SCHEMBL11886594 | 0.71 | MAOB (0.71) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL22501738 | 0.71 | RAB9A (0.76) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL7434428 | 0.70 | MAOB (0.70) | MAOBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL121310 | 0.70 | MAOB (0.70) | MAOBNPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102040592-B | Coumarin azole compound with antimicrobial activity, and preparation method and medicinal application thereof | UNIV SOUTHWEST | 2015-07-15 | — | — | CN | claimed |