Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854642 | 0.81 | MAPT (0.63) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| Hydrochloric Acid SCHEMBL30468417 | 0.80 | MAPT (0.61) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| Hydrochloric Acid SCHEMBL29051918 | 0.80 | MAPT (0.61) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL2570160 | 0.80 | KDM4E (0.61) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL27886320 | 0.79 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL30415039 | 0.78 | LMNA (0.58) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL19287492 | 0.78 | MAPT (0.58) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL1738690 | 0.77 | GRM2 (0.45) | SMN1; SMN2NPC1RAB9AHTR6ALDH1A1 | |
| SCHEMBL265040 | 0.76 | MAPT (0.69) | MAPTSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL10016535 | 0.75 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |