Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28004658 | 0.88 | ALDH1A1 (0.65) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Benzene SCHEMBL28101078 | 0.86 | ALDH1A1 (1.00) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| SCHEMBL960 | 0.86 | ALDH1A1 (1.00) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| SCHEMBL27316763 | 0.84 | ALDH1A1 (0.96) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28006384 | 0.84 | ALDH1A1 (0.96) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Hydrogen Sulfide SCHEMBL27839115 | 0.84 | ALDH1A1 (0.96) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| SCHEMBL28942580 | 0.84 | ALDH1A1 (0.96) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Pyridine SCHEMBL4372448 | 0.83 | ALDH1A1 (0.79) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Methane SCHEMBL29164406 | 0.82 | ALDH1A1 (0.92) | ALDH1A1POLBL3MBTL1TDP1KMT2A | |
| Methylene Chloride SCHEMBL27704382 | 0.82 | ALDH1A1 (0.92) | ALDH1A1POLBL3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797584-A | Tricyclic heterocyclic compounds as notch inhibitors | BRISTOL MYERS SQUIBB CO | 2015-07-22 | — | — | CN | disclosed |