Biphenyl

Biphenyl

SCHEMBL28023256

O=S(=O)(Oc1cnccn1)C(F)(F)F.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 3/20 0.42
PDE4C Q08493 3/20 0.42
PDE4D Q08499 3/20 0.42
PTGS2 P35354 5/20 0.37
PTGS1 P23219 5/20 0.37
GAA P10253 1/20 0.36
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
CYP19A1 P11511 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
CYP2A6 P11509 1/20 0.33
CA12 O43570 1/20 0.33
NAAA Q02083 1/20 0.33
SLC6A7 Q99884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27141135 0.91 KDM4E (0.37) PDE4APDE4CPDE4DPTGS2PTGS1
SCHEMBL29506049 0.91 KDM4E (0.37) PDE4APDE4CPDE4DPTGS2PTGS1
SCHEMBL31090281 0.80 PDE4A (0.45) PDE4APDE4CPDE4DADORA2AADORA1
SCHEMBL1018963 0.78 PDE4A (0.41) PDE4APDE4CPDE4DADORA2AADORA1
SCHEMBL538501 0.77 PDE4A (0.44) PDE4APDE4CPDE4DPTGS2PTGS1
SCHEMBL28023254 0.74 PDE4A (0.41) PDE4APDE4CPDE4DADORA2AADORA1
SCHEMBL9172136 0.74 CA1 (0.51) CYP19A1CA1CA2CA9ALDH1A1
SCHEMBL16751245 0.74 PDE4A (0.46) PDE4APDE4CPDE4DADORA2AADORA1
SCHEMBL6293150 0.73 CYP2A6 (0.45) PDE4APDE4CPDE4DKDM4EALDH1A1
SCHEMBL16738294 0.73 PDE4D (0.47) PDE4APDE4CPDE4DADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104672152-A Organic compound and use thereof in synthesis of organometallic complex SEMICONDUCTOR ENERGY LAB 2015-06-03 CN disclosed