Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634084 | 0.83 | POLB (0.52) | POLBEGFRHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL21047951 | 0.83 | POLB (0.52) | POLBEGFRHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL27150096 | 0.80 | POLB (0.49) | POLBEGFRHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL9431344 | 0.79 | POLB (0.47) | POLBEGFRKMT2AL3MBTL1PTPRC | |
| SCHEMBL23092860 | 0.77 | POLB (0.55) | POLBHSD17B10KMT2ACA12CA1 | |
| SCHEMBL29715410 | 0.77 | POLB (0.55) | POLBHSD17B10KMT2ACA12CA1 | |
| SCHEMBL29114639 | 0.77 | CA12 (0.57) | POLBEGFRHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL27552976 | 0.77 | POLB (0.46) | POLBEGFRHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL10679407 | 0.77 | POLB (0.64) | POLBHSD17B10KMT2AL3MBTL1PTPRC | |
| SCHEMBL778637 | 0.77 | BACE1 (0.42) | POLBHSD17B10KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174862-B | Synthesis method of benzyl sulfide | 成都理工大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-104902894-A | Benzoxazolinone compounds with selective activity in voltage-gated sodium channels | MERCK SHARP & DOHME | 2015-09-09 | — | — | CN | disclosed |