SCHEMBL280236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL276955	0.84	ALDH1A1 (0.58)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL277890	0.82	KMT2A (0.55)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL14625162	0.80	POLB (0.45)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL2638143	0.80	ALDH1A1 (0.51)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL280023	0.80	POLB (1.00)	POLBTDP1KMT2AMAPTALDH1A1
	SCHEMBL14986443	0.80	GAA (0.67)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL1106560	0.80	KMT2A (0.65)	POLBTDP1KMT2AKDM4EALDH1A1
	SCHEMBL14986345	0.80	POLB (0.65)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL12313375	0.77	KMT2A (0.66)	POLBTDP1KMT2AKDM4EMAPT
	SCHEMBL13402903	0.77	POLB (0.61)	POLBTDP1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.