Mannitol

Mannitol

SCHEMBL28023612

NC(=O)O.OCC(O)C(O)C(O)C(O)CO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.65
SLCO1B1 Q9Y6L6 1/20 0.65
LMNA P02545 2/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
PDE4A P27815 1/20 0.64
TDP1 Q9NUW8 1/20 0.61
KDM4E B2RXH2 2/20 0.44
ACHE P22303 1/20 0.41
OR51E2 Q9H255 1/20 0.41
TGFBR1 P36897 1/20 0.34
MGAM O43451 3/20 0.33
SI P14410 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL1504919 0.91 LMNA (0.69) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL28204430 0.91 LMNA (0.69) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL30410531 0.88 LMNA (0.73) USP2SLCO1B1LMNAL3MBTL1PDE4A
Sorbitol SCHEMBL31013480 0.88 LMNA (0.73) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL27844169 0.88 LMNA (0.73) USP2SLCO1B1LMNAL3MBTL1PDE4A
E968 SCHEMBL9363265 0.88 USP2 (0.50) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL28980368 0.86 LMNA (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL29235000 0.86 LMNA (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
Xylitol SCHEMBL4750185 0.85 LMNA (0.59) USP2SLCO1B1LMNAL3MBTL1PDE4A
Mannitol SCHEMBL31441251 0.85 LMNA (0.69) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989575-B Degradable high-strength plastic packaging bag and preparation method thereof 山东蓝海晶体科技有限公司 2024-01-12 CN disclosed
CN-114989575-A Degradable high-strength plastic packaging bag and preparation method thereof 张明晨 2022-09-02 CN disclosed
CN-104903341-A Substituted anionic compounds consisting of a backbone consisting of discrete number of saccharide units ADOCIA 2015-09-09 CN disclosed