Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820991 | 0.89 | PKLR (0.64) | PKLR | |
| SCHEMBL28023218 | 0.84 | PKLR (0.58) | PKLR | |
| SCHEMBL28820934 | 0.84 | PKLR (0.68) | PKLR | |
| SCHEMBL16049700 | 0.78 | PKLR (0.81) | PKLR | |
| SCHEMBL28023239 | 0.78 | PKLR (0.64) | PKLR | |
| SCHEMBL16049593 | 0.77 | PKLR (0.52) | PKLR | |
| SCHEMBL16050784 | 0.73 | PKLR (0.88) | PKLR | |
| SCHEMBL21976367 | 0.72 | PKLR (0.61) | PKLR | |
| SCHEMBL16049648 | 0.70 | PKLR (0.82) | PKLR | |
| SCHEMBL28820989 | 0.69 | PKLR (0.60) | PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121425-A | Therapeutic compounds and compositions | AGIOS PHARMACEUTICALS INC | 2015-12-02 | — | — | CN | disclosed |