Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007452 | 0.82 | CYP19A1 (1.00) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL151053 | 0.82 | CYP19A1 (1.00) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| Bromide SCHEMBL28888744 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| Ammonia Solution, Strong SCHEMBL29210102 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9398256 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10659676 | 0.80 | P2RX4 (0.51) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10660950 | 0.80 | P2RX4 (0.59) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL29904927 | 0.79 | P2RX4 (1.00) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14160818 | 0.79 | P2RX4 (1.00) | CYP19A1P2RX4KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL13957035 | 0.76 | CYP19A1 (0.86) | CYP19A1P2RX4CYP1A2CYP2C19HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744340-A | Polysubstituted carbazole compound, preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |