Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 1.00 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151053 | 1.00 | CYP19A1 (1.00) | CYP19A1P2RX4SMN1; SMN2LMNACYP1A2 | |
| Bromide SCHEMBL28888744 | 0.98 | CYP19A1 (0.95) | CYP19A1P2RX4SMN1; SMN2LMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL29210102 | 0.98 | CYP19A1 (0.95) | CYP19A1P2RX4SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9398256 | 0.98 | CYP19A1 (0.95) | CYP19A1P2RX4SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL13957035 | 0.93 | CYP19A1 (0.86) | CYP19A1P2RX4CYP1A2CYP2C19HDAC6 | |
| SCHEMBL17104579 | 0.90 | CYP19A1 (0.81) | CYP19A1P2RX4SMN1; SMN2LMNAMEN1 | |
| SCHEMBL17112767 | 0.90 | CYP19A1 (0.81) | CYP19A1P2RX4SMN1; SMN2LMNAMEN1 | |
| Acetic Acid SCHEMBL9519258 | 0.88 | CYP19A1 (0.78) | CYP19A1P2RX4SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL8154947 | 0.87 | CYP19A1 (0.77) | CYP19A1P2RX4CYP1A2CYP2C19HDAC6 | |
| SCHEMBL29904927 | 0.87 | P2RX4 (1.00) | CYP19A1P2RX4SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220370411-A1 | EARLY MANAGEMENT, MITIGATION and PREVENTION OF SEPSIS and SEPSIS-LIKE SYNDROMES, INCLUDING NEO-NATAL ARDS DUE TO INFECTION, INJURY or IATROGENESIS | OPHIREX INC (US) | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220370411-A1 | EARLY MANAGEMENT, MITIGATION and PREVENTION OF SEPSIS and SEPSIS-LIKE SYNDROMES, INCLUDING NEO-NATAL ARDS DUE TO INFECTION, INJURY or IATROGENESIS | PLA2G12A, PLA2G3, PLA2G1B | CYP19A1 2391/4885P2RX4 2655/4885SMN1; SMN2 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.