SCHEMBL28024012

SCHEMBL28024012

CCOP(=O)(OCC)OCC(=O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PPARD Q03181 2/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
GAA P10253 1/20 0.33
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
POLB P06746 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethyl Phosphate SCHEMBL28108275 0.80 TSHR (0.62) TSHRCYP3A4CYP2C9CYP2C19TP53
Triethyl Phosphate SCHEMBL22685846 0.78 TSHR (0.59) TSHRCYP3A4CYP2C9CYP2C19TP53
SCHEMBL27771235 0.76 TSHR (0.62) TSHRCYP3A4CYP2C9CYP2C19TP53
SCHEMBL9558848 0.76 TPI1 (0.46)
SCHEMBL11296124 0.76
Triethyl Phosphate SCHEMBL10358522 0.74 TSHR (0.77) TSHRCYP3A4CYP2C9CYP2C19TP53
SCHEMBL28065638 0.74 TSHR (0.59) TSHRCYP3A4TP53TDP1PPARD
SCHEMBL28308540 0.74 TSHR (0.59) TSHRCYP3A4CYP2C9CYP2C19TP53
Triethyl Phosphate SCHEMBL1332591 0.74 TSHR (1.00) TSHRCYP3A4TP53TDP1PPARD
Triethyl Phosphate SCHEMBL28023664 0.74 TSHR (1.00) TSHRCYP3A4TP53TDP1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104693087-A 24, 28-ene-1alpah-hydroxyl vitamin D derivatives and preparation method thereof UNIV NANJING SCIENCE & TECH 2015-06-10 CN claimed
CN-104693087-A 24, 28-ene-1alpah-hydroxyl vitamin D derivatives and preparation method thereof UNIV NANJING SCIENCE & TECH 2015-06-10 CN disclosed