Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804353 | 1.00 | FAAH (0.63) | FAAHCYP19A1CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL2227448 | 0.93 | HRH3 (0.60) | FAAHCYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL29678370 | 0.93 | HRH3 (0.60) | FAAHCYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL27912351 | 0.93 | FAAH (0.56) | FAAHCYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL1482500 | 0.92 | HRH3 (0.60) | FAAHHRH3KCNJ1KCNH2DRD4 | |
| SCHEMBL17683623 | 0.92 | FAAH (0.56) | FAAHCYP19A1CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL29809149 | 0.92 | HRH3 (0.60) | FAAHHRH3KCNJ1KCNH2DRD4 | |
| SCHEMBL29809589 | 0.91 | HRH3 (0.62) | FAAHCYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL13834236 | 0.91 | HRH3 (0.62) | FAAHCYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL2228790 | 0.91 | HRH3 (0.62) | FAAHCYP19A1CYP11B1CYP11B2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025816-B | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORP | 2015-07-22 | — | — | CN | disclosed |