SCHEMBL28024192

SCHEMBL28024192

O=S(=O)(O)c1cccc2nc(I)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.43
CYP1A2 P05177 3/20 0.38
FABP4 P15090 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
MAPK14 Q16539 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NR4A1 P22736 1/20 0.36
ATIC P31939 1/20 0.35
COMT P21964 1/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
TET2 Q6N021 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CHAT P28329 1/20 0.34
SNCA P37840 1/20 0.34
TNNI3 P19429 1/20 0.34
TNNT2 P45379 1/20 0.34
TNNC1 P63316 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519973 0.82 TTR (0.46) TTRCYP1A2FABP4CCNA2CDK2
SCHEMBL1534731 0.81 CYP1A2 (0.45) TTRCYP1A2FABP4CCNA2CDK2
SCHEMBL13233369 0.79 ALDH1A1 (0.49) TTRCYP1A2FABP4CCNA2CDK2
Water SCHEMBL8533341 0.79 CYP1A2 (0.44) TTRCYP1A2FABP4CCNA2CDK2
SCHEMBL31091510 0.76 NPC1 (0.50) TTRCYP1A2FABP4CCNA2CDK2
SCHEMBL1502472 0.72 TTR (0.72) TTRCYP1A2CDK2TSHRSMN1; SMN2
SCHEMBL8028660 0.72 TTR (0.72) TTRCYP1A2CDK2TSHRSMN1; SMN2
SCHEMBL305631 0.72 TTR (0.72) TTRCYP1A2CDK2TSHRSMN1; SMN2
SCHEMBL30272856 0.72 ALDH1A1 (0.51) TTRCYP1A2FABP4CCNA2CDK2
SCHEMBL329215 0.72 ALDH1A1 (0.51) TTRCYP1A2FABP4CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110289357-A Organic photo-thermal composite, preparation method and application and light thermoelectric cell and light delay control system 西南交通大学 2019-09-27 CN disclosed
CN-107326348-A A kind of method and related chemistry copper plating bath that core inductance quality value is lifted based on chemical plating Porous Cu 电子科技大学 2017-11-07 CN disclosed
CN-106661734-A Method for manufacturing wiring substrate and wiring substrate manufactured thereby 上村工业株式会社 2017-05-10 CN disclosed
CN-103789764-B The manufacture method of semiconductor element, semiconductor element 三菱电机株式会社 2016-06-08 CN disclosed
CN-102406964-B Flexible bone composite material and preparation method thereof Sinsis (USA) Co. (US) 2015-08-05 CN disclosed