Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904960 | 0.76 | NPC1 (0.56) | RAB9ANPC1TLR9ALDH1A1MAPT | |
| SCHEMBL18230290 | 0.69 | TLR9 (0.56) | RAB9ANPC1TLR9JAK2ALDH1A1 | |
| SCHEMBL27605458 | 0.69 | HTT (0.55) | RAB9ANPC1CYP2C9LMNAJAK2 | |
| SCHEMBL11261266 | 0.68 | ALOX5AP (0.51) | RAB9ANPC1JAK2ALDH1A1MAPT | |
| SCHEMBL27623777 | 0.66 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1CYP3A4MAPT | |
| SCHEMBL27742121 | 0.66 | KDM4E (0.41) | RAB9ANPC1CYP2C9TLR9ALDH1A1 | |
| SCHEMBL13495699 | 0.65 | NPC1 (0.68) | RAB9ANPC1TLR9ALDH1A1CYP3A4 | |
| SCHEMBL6291686 | 0.65 | NPC1 (0.53) | RAB9ANPC1TLR9ALDH1A1MAPT | |
| SCHEMBL1464105 | 0.65 | NPC1 (1.00) | RAB9ANPC1LMNATLR9JAK2 | |
| SCHEMBL29614829 | 0.63 | NPC1 (0.63) | RAB9ANPC1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797246-A | Telomerase inhibitors for use in therapy | AGENCY SCIENCE TECH & RES | 2015-07-22 | — | — | CN | disclosed |