SCHEMBL28024468

SCHEMBL28024468

NNc1ccccc1-c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
HPGD P15428 2/20 0.44
BCL2L1 Q07817 1/20 0.44
BACE1 P56817 1/20 0.41
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
DPP4 P27487 1/20 0.40
CYP2A6 P11509 1/20 0.39
MAPK1 P28482 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP2C9 P11712 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192231 0.91 ALDH1A1 (0.48) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
Hydrochloric Acid SCHEMBL4377886 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
Methane SCHEMBL28503055 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL11817898 0.85 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1MAPK1
SCHEMBL16616882 0.81 FABP3 (0.57) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL30302966 0.79 FABP3 (0.60) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL11817908 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL5016493 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL24816075 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1
SCHEMBL21671133 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10SIGMAR1HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104803880-A Compound with neuroprotective effect and preparation method and application thereof GUANGZHOU MAGPIE PHARMACEUTICAL CO LTD 2015-07-29 CN disclosed