SCHEMBL28024611

SCHEMBL28024611

COc1ccc2c(c1)c(-c1ccc(S(=O)(=O)O)cc1)cn2-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 2/20 0.51
MTNR1A P48039 1/20 0.49
MTNR1B P49286 1/20 0.49
HTR6 P50406 9/20 0.48
PPARG P37231 2/20 0.43
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
ESRRA P11474 1/20 0.43
KDM4E B2RXH2 2/20 0.43
PLA2G4A P47712 1/20 0.43
PTGS2 P35354 1/20 0.43
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
HTR1A P08908 1/20 0.42
DRD2 P14416 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
HTR1E P28566 1/20 0.42
HTR1F P30939 1/20 0.42
HTR7 P34969 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024129 0.82 HTR6 (0.51) PTPN11HTR6KDM4EHTR7HPGD
SCHEMBL18552151 0.78 KDR (0.52) PTPN11HTR6ESRRAMAPTHPGD
SCHEMBL18552150 0.76 BRD4 (0.46) PTPN11HTR6PLA2G4AMAPT
SCHEMBL1171595 0.74 ESRRA (0.52) PTPN11ESRRAMAPTHPGD
SCHEMBL19737472 0.74 HTR6 (0.66) HTR6HTR1ADRD2HTR1DHTR1B
SCHEMBL18552051 0.73 KDR (0.50) PTPN11HTR6ESRRAPLA2G4AMAPT
SCHEMBL18552136 0.73 KDR (0.47) PTPN11HTR6ESRRAKDM4EMAPT
SCHEMBL28024588 0.72 HTR6 (0.51) MTNR1AMTNR1BHTR6KDM4EPLA2G4A
SCHEMBL19737629 0.72 HTR6 (0.58) HTR6PPARGPPARDPPARAHTR1A
Dimethylamine SCHEMBL21222407 0.71 HTR6 (0.65) HTR6HTR1ADRD2HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104803817-A Method for synthesizing arenesulphonate compound UNIV SHANGHAI 2015-07-29 CN disclosed